Contains information about tVNS clinical research devices tVNS® R for Research Discover a Revolutionary Journey with Innovative tVNS® Research Device Meet the cutting-edge realm of vagus nerve stimulation research, where innovation meets precision in our state-of-the-art tVNS® R device. Crafted for flexibility and accuracy, it boasts complete wireless programmability, making it the perfect companion for in-depth clinical studies. Experience seamless control with the tVNS® Research and tVNS® Patient apps, integrating stimulation parameter adjustments, data collection, and patient feedback to elevate the depth and precision of your research. Our commitment extends beyond technology; we're here to streamline your clinical trials, providing robust support for your studies, including a thorough CB safety report for swift ethics approvals and access to a global network of experts. Uncover the limitless potential of tVNS® R as it pioneers revolutionary paths in neurological research and transforms the landscape of patient care. Your journey to groundbreaking discoveries starts here. tVNS® R for Research Transcutaneous Vagus Nerve Stimulation Device for Research Full Wireless Parameter Programmability Patient App for Data Collection Support for Clinical Trials Triggered tVNS® Legacy and Hook Electrode Sham Stimulation Research and Patient App Your tVNS® R device gives you access to two apps: the tVNS® Research and tVNS® Patient app. All technical parameters can easily be reprogrammed and wirelessly transmitted with the tVNS® Research app, allowing the researcher to try completely new stimulation protocols. In addition, you can collect and store technical and patient data. The tVNS® Patient app automatically stores all technical data (stimulation parameters, time and duration of the stimulation etc.) and offers a questionnaire for patient feedback. Support for Clinical Trials We offer an individual adaptation of all parts for certain studies, e.g by changing the questionnaire in order to allow better feedback from the patient, or through the implementation of special stimulation parameters or technical ideas. The tVNS® R device is defined as a device for investigational use. We can provide a CB report that proves the safety according to all medical device standards, in order to assist you with ethics approvals. So far, it has been accepted by all ethics committees. In addition, we offer an international expert network and can direct any questions to experienced people around the world. Triggered tVNS® We offer a separate PC-based tVNS® manager software. This software enables reaction to outside trigger signals (e.g. ECG R-wave trigger generated by an external ECG system, transferred to a PC). Thus, closed loop tVNS® or triggered tVNS® can be realized in a scientific setup. Legacy and Hook Electrode We offer two different types of electrode designs with our tVNS® devices: The Hook Electrode (left) comes standard with all new tVNS® devices. It offers bet ter fixation and usability during daily activities. The Legacy Electrode (right) can be used if the patient has small ears or a special ear shape. The integrated slider allows for better adaption to the ear. Sham Stimulation The well known sham stimulation at the ear lobe is still possible. Upon request, we support studies by providing other more sophisticated sham stimulation options.

tVNS, non-surgical treatment option for epilepsy. The most up-to-date health information about epilepsy causes, symptoms, treatment options Less seizures - more from life. Treat drug-resistant epilepsy wit h tVNS® Epilepsy An epileptic seizure is a clinical condition that occurs when the normal activity of the brain is disrupted by the temporary abnormal electrical acti vity in the nerve cells. Epilepsy is the recurrence of epileptic seizures and is considered a chronic disease. While anticonvulsants are commonly prescribed, many epileptic patients are resist ant to drug therapy. Treatment Options for Drug Resistant Epilepsy Epilepsy Surgery There are two methods of neurosurgery: removal of the brain region that causes seizures and surgical cutting of the neural pathways that cause seizures to spread. However, since these methods are only suitable for focal epilepsies, only a small proportion of epilepsy patients are suitable for this invasive procedure. In deep brain stimulation, electrodes are implanted in the brain. These electrodes are attached to a battery operated stimulator that is usually placed under the patient’s collarbone. Epileptic activity can be specifically affected at the baseline through current stimuli. Deep Brain Stimulation Invasive Vagus Nerve Stimulation In some patients, a treatment called “vagus nerve stimulation”, also known as brain pacemaker surgery, can be applied. With a surgical intervention, a battery is placed under the chest and an electrode wire is placed in the vagus nerve in the neck. With the help of the electrode, the vagus nerve is stimulated at regular intervals, which may reduce seizures. Transcutaneous Vagus Nerve Stimulation The tVNS® auricular vagus nerve stimulation device is a treatment option that provides vagus nerve stimulation through the ear with a smartphone-sized device and a special headset without any surgical intervention. From there, as with invasive vagus nerve stimulation, higher centers of the brain are activated, triggering an anticonvulsant effect. How does tVNS® treat epilepsy? In transcutaneous vagus nerve stimulation, mild electrical impulses are given to the cymba concha region in the outer auricle through a special ear electrode. These stimuli activate the vagus nerve, which passes directly under the skin in this region (auricular branch of the vagus nerve). The nerve first transmits these impuleses to the Nucleus Tractus Solitarius in the brain stem and are transmitted to many different regions of the diencephalon (midbrain) and cerebrum. These stimuli are also transmitted to the Norepinephrine (Noradrenaline) center, the Locus Coeruleus, and Serotonin center, the Dorsal Raphe nucleus. These transmitters affect one’s clarity, energy, and confidence. These 2 centers send these neurotransmitters to the entire brain, specifically to the parts that control thinking and feeling. more serotonin and norepinephrine are then sent to the Prefrontal Cortex and are inhibited in the Hippocampus and Anterior Thalamus regions, which reduces anxiety and panic. This mechanism causes the frequency or severity of seizures to be reduced or stopped entirely. tVNS has helped hundreds of patients suffering from epilepsy to reduce or completely eliminate their seizures and lead a more self-determined life, without the need for surgery. “It’s wonderful that with tVNS® I have found a therapy option that makes me feel better without needing surgery.” Katja S. from Munich

< Back Long-term benefits of clean energy sources Kim Jennings Mar 20, 2023 This is placeholder text. To change this content, double-click on the element and click Change Content. This is placeholder text. To change this content, double-click on the element and click Change Content. Want to view and manage all your collections? Click on the Content Manager button in the Add panel on the left. Here, you can make changes to your content, add new fields, create dynamic pages and more. Your collection is already set up for you with fields and content. Add your own content or import it from a CSV file. Add fields for any type of content you want to display, such as rich text, images, and videos. Be sure to click Sync after making changes in a collection, so visitors can see your newest content on your live site. Previous Next

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TVNS treatment in Crohn's disease. The most up-to-date health information on crohn's disease causes, symptoms, treatment options Crohn's Disease Groundbreaking Technologies for Life What is Crohn's Disease ? Crohn's disease is a type of inflammatory bowel disease that causes inflammation of the gastrointestinal tract from the mouth to the anus. This inflammation can be attached to one or more parts of the digestive system, but it is usually seen in the ileum, which is the last part of the small intestine, and in the beginning of the large intestine. Crohn's disease can cause inflammation in your digestive tract, leading to abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition. Growth-development retardation in children may be signs of Crohn's disease. Extra-intestinal diseases are also observed in a quarter of Crohn's patients. These mostly occur in the skin, joints, eyes, liver and biliary tract, kidney and urinary tract, vascular heart and lungs. Crohn's Disease Symptoms Diarrhea Abdominal pains Intestinal blockages Fever Fatigue Loss of appetite and weight loss Still feeling full after using the toilet Frequent toileting is one of the early symptoms of Crohn's disease. Insomnia Tanı Yöntemleri Crohn's Disease Causes Immune system: It is possible for a virus or bacteria to trigger Crohn's disease; however, scientists have yet to identify such a trigger. When your immune system tries to fight off the invading microorganism, an abnormal immune response can cause the immune system to attack cells in the digestive tract as well. Heredity: Crohn's disease is more common in people with a family history of the same disease, so genes may play a role in the occurrence of the disease. Crohn's Disease Diagnostic Methods Blood analysis Stool analysis Stomach, small and large intestine films Colonoscopy and endoscopy CT and MRI images Crohn's disease can occur at any age, but it usually occurs when the disease is young. Most people who develop Crohn's disease are diagnosed before they reach the age of about 30. You are at higher risk for the disease if you have a first-degree relative with the disease, such as a parent, sibling, or child. About 1 in 5 people with Crohn's disease have a family member with the disease. Facts About Crohn's Disease Treatment Options for Crohn's Disease Medication Steroid drugs: These are drugs to reduce inflammation in the digestive system. Drugs for the immune system: These are drugs used to control the immune system. More information Surgical treatment Most Crohn's Disease patients may need surgical treatment. Removing the problematic parts of the digestive system and reconnecting them to healthy parts is the aim of surgical treatment. More information Crohn's Disease Diet In general, the patient is given a high-energy, abundant protein, low-fiber, low-fat diet rich in vitamins and minerals. For some patients, consumption of milk and dairy products is prohibited. More information Transcutaneous Vagus Nerve Stimulation (tVNS) tVNS ® reduces inflammation in the intestine, allowing the intestine to do its job more healthily. More information Contact us

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Drug-free non-surgical tvns vagal nerve stimulation in the treatment of tinnitus. The most up-to-date health information on tinnitus causes, symptoms, treatment options Tinnitus Tinnitus and Vagus Nerve Stimulation Tinnitus can also be defined as the patient's perception of a sound without an acoustic stimulus. This sound can have different tones, features and characters. The sound most often heard as ringing is sometimes described as humming, bells, wind or whistling, machinery noise, rustling, pulsing sounds. Tinnitus is considered as a symptom rather than a disease and is treated as such. It is the most common symptom of the auditory system. These complaints may be severe enough to cause mental problems or severely impair the quality of life, and in some people, tinnitus may come and go within a few minutes. Clinical studies have shown that vagus nerve stimulation provides an increase in parasympathetic activity, calms the patient, reduces sleep disorders due to tinnitus, and decreases THI (Tinnitus Handicap Inventoy). For more detailed information, please contact tVNS Turkey. Contact us